I … bitter, bitten, bitterly, bitterness " bittner milk factor " : exemples et traductions en contexte And a few years later, Keith Porter et al. Juli 1941 in Gleiwitz/Oberschlesien) ist ein deutscher Schriftsteller.

Next, Bittner took babies from the immune Family B and set them to nurse with cancerous mothers from Family A. Plus de fonctionnalités. is a reliable and trustworthy business partner. In various embodiments of the present invention, compositions comprising beta-alanyl-L-histidine (carnosine) or derivatives or analogs thereof and basic milk factor (BMF) for prophylaxis and treatment of aged or photodamaged, or damaged, as in wounded or disrupted, skin. The Bittner virus is now known as the Mouse mammary tumor virus (MMTV), a retrovirus. (see Timeline of Discovery 1936 under Oncovirus).

Utilisez le dictionnaire Anglais-Français de Reverso pour traduire bittner milk factor et beaucoup d’autres mots. In 1966, it was proven that Bittner's "milk factor" was a virus that remained dormant during the early life of the young mouse but produced cancer when hormonal conditions were right in middle age. [1][2] The majority of mammary tumors in mice are caused by mouse mammary tumor virus. This DNA intermediate state of the virus is called the provirus. HHS During the summer of 1947, he was a member of the Medical Teaching Mission to Austria, sponsored by the Unitarian Service Committee, of the World Health Organization to "promote international exchange of medical and scientific knowledge.". "Making Mice Standardizing Animals For American Biomedical Research 1900-1955" Princeton University Press (2004), "University of Minnesota, Institute for Molecular Virology, UMN Virology Timeline", "Obituary, John Joseph Bittner, 1904-1961", https://en.wikipedia.org/w/index.php?title=John_Joseph_Bittner&oldid=955451123, Creative Commons Attribution-ShareAlike License, 1941 The Alvarenga Award - American College of Physicians in Philadelphia, 1950 Honorary Doctor of Science Degree - Bard College, Annandale-on-Hudson, New York, 1951 1st Comfort Crookshank Award - Middlesex Hospital Medical School, London, 1957 Bertner Foundation Award - M.D. Cultivation of the mouse mammary carcinoma virus. It belongs to the genus Betaretrovirus. Bittner used two families of mice: in Family A, almost all the mice, across many generations, developed breast cancer; in Family B, cancer seldom occurred. J Albert Einstein Med Cent (Phila). Clipboard, Search History, and several other advanced features are temporarily unavailable. [9] In addition the expression of the genome is activated specifically in the mammary gland cells. factory techniques of study in order to make such contributions meaningful. NLM Continuing to use this site, you agree with this. These leukemias are active when cells are transferred to other mice. Throughout his career, Bittner served on numerous committees dealing with cancer research. Temps écoulé: 300 ms. Mots fréquents: 1-300, 301-600, 601-900, Plus, Expressions courtes fréquentes: 1-400, 401-800, 801-1200, Plus, Expressions longues fréquentes: 1-400, 401-800, 801-1200, Plus. This glucocorticoid element is a promoter that is often used to construct mice which develop a breast cancer-like disease, because an animal model system for breast cancer close to the human disease is very much looked for.

1961;8:225-36. [Cultivation of the milk factor (Bittner's virus) in vitro]. Autres définitions en rapport: acidophilus lait; antialopecia facteur; facteur antihémophilique B; facteur d'accélération; B-cell facteur stimulant 2 Dictionnaire Collaboratif     Anglais-Français, 1) (use, drain out) extraire ; exploiter ; presser comme un citron 2) (use little at a time) extraire ; prélever ; ponctionner ; utiliser au compte-goutte, affacturer (vt.) ; prendre en compte (vt.). You're scared of the neighbor's dog? NIH OK. The MMTV-PyMT model has been shown to be a reliable model of breast cancer metastasis. [6], As a retrovirus the mouse mammary tumor virus (MMTV) is able to insert its viral genome in the host genome. The Bittner virus is now known as the Mouse mammary tumor virus (MMTV), a retrovirus. Bittner was born in Meadville, Pennsylvania, on February 25, 1904, the son of the late Martin and Minnie Bittner. May I have an itty-bitty bite of your salmon? Les traductions vulgaires ou familières sont généralement marquées de rouge ou d’orange. A number of large-scale projects completed in Poland, high competitiveness and innovative character of our products certifiy that Cable Factory BITNER Sp. PMID: 13723282 [13] In human breast cancer the polyoma middle T- antigen was not found.

[citation needed], The MMTV promoter is used in the PyMT model system of mouse models of breast cancer metastasis. His Ph.D. thesis was entitled "A Genetic Study of the Transplantation of Tumors Arising in Hybrid Mice.". As a young man he was so proficient in baseball, basketball, and track that he received offers of athletic scholarships at several schools. [Cultivation of the milk factor (Bittner's virus) in vitro]. See also: bitty, itty itty-bitty Very small or petite; tiny. Neoplasma. Several mouse strains carry the virus endogenously, but it is also transmitted vertically via milk from mother to pup. Als Bovine Meat and Milk Factors (BMMF) werden DNA-Bestandteile in Rindfleisch und Kuhmilch bezeichnet, die für die Entstehung von Krebs (insbesondere Darmkrebs und Brustkrebs) verantwortlich sein könnten. degree in 1929, and his Ph.D. in 1930. While there he received his M.S.

Suggérer un exemple . Here Py is the abbreviation of polyoma and MT is the abbreviation for middle T. There are more model systems of breast cancer which use the MMTV promoter. If the virus is transferred exogenously, it is passed from the mother mouse to her pups through her milk. Bittner received many awards, citations, and medals during his career. In addition, Bittner felt that genetic and hormonal influences, along with the milk agent, contributed to the origin of cancer. [10], The LTR (long terminal repeat) of MMTV contains a glucocorticoid hormone response element. 1960. The virus RNA genome is reverse transcribed by reverse transcriptase into DNA. Notre définition de Facteur de lait de Bittner: virus de tumeurs mammaires de souris.

[12], When the mouse reaches puberty the virus begins to express its messenger RNA in the estrogen sensitive tissues. See B. agent, B. milk factor (see Timeline of Discovery 1936 under Oncovirus). He taught at Donaldson Preparatory School, Ilchester, Maryland, for one year before beginning graduate work at the University of Michigan. Pour ajouter des entrées à votre liste de, Voir plus d'exemples de traduction Anglais-Français en contexte pour “, Apprenez l’anglais, l’espagnol et 5 autres langues gratuitement, Reverso Documents : traduisez vos documents en ligne, Expressio : le dictionnaire d'expressions françaises, Apprenez l'anglais avec vos vidéos préférées, And a few years later, Keith Porter et al. Come on, Catherine, just try an itty bitty bite—if you don't like it, you don't have to eat the rest. When the virus DNA is inserted inside or even near an oncogene, it is able to change the expression of that gene and cause cancer. © 2013-2020 Reverso Technologies Inc. All rights reserved. He also served on the editorial advisory board of Cancer Research from 1941-1957. This site needs JavaScript to work properly. had a similar success in imaging the ", Et quelques années plus tard, Keith Porter et ses associés ont eu un succès similaire en obtenant des images du ", In various embodiments of the present invention, compositions comprising beta-alanyl-L-histidine (carnosine) or derivatives or analogs thereof and basic, Divers modes de réalisation de la présente invention concernent des compositions contenant de la bêta-alanyl-L-histidine (carnosine) ou des dérivés ou des analogues de celle-ci, et un, this invention relates to a method for treating skin damage, comprising the step of administration of a pharmaceutical or dermatological composition of basic, la présente invention concerne un procédé pour traiter des dommages cutanés. Bittner authored, or co-authored, over 240 papers on cancer research, and contributed chapters to several books. 1. Mouse mammary tumor virus (MMTV) is a milk-transmitted retrovirus like the HTL viruses, HI viruses, and BLV. J Albert Einstein Med Cent (Phila). It is contained as a DNA provirus integrated in the DNA of milk lymphocytes. [citation needed], Endogenous MMTV reacts to the whole range of hormones that regulate normal mammary development and lactation, response has been demonstrated to steroid hormones (androgens, glucocorticoids and progestins),[11] as well as prolactin. The most notable include the following: Ruddy, Kathleen T, MD "The End of Breast Cancer: A Virus and the Hope for a Vaccine" Skyhorse Publishing Inc (2017)(Previously published as "Of Mice and Women: Unraveling the Mystery of the Breast Cancer Virus") (2015), Rader, Karen A. John J., U.S. oncologist, 1904–1961. Mouse mammary tumor virus (MMTV) is a milk-transmitted retrovirus like the HTL viruses, HI viruses, and BLV. Vous pouvez compléter la traduction de bittner milk factor proposée par le dictionnaire Collins Anglais-Français en consultant d’autres dictionnaires spécialisés dans la traduction des mots et des expressions : Wikipedia, Lexilogos, Oxford, Cambridge, Chambers Harrap, Wordreference, Collins, Merriam-Webster ... Dictionnaire Anglais-Français : traduire du Anglais à Français avec nos dictionnaires en ligne. MMTV was formerly known as Bittner virus, and previously the "milk factor", referring to the extra-chromosomal vertical transmission of murine breast cancer by adoptive nursing, demonstrated in 1936, by John Joseph Bittner while working at the Jackson Laboratory in Bar Harbor, Maine. [6], MMTV can be transferred either through an exogenous or endogenous route. Bittner established the theory that a cancerous agent, or "milk factor", could be trans… Vous souhaitez rejeter cette entrée : veuillez indiquer vos commentaires (mauvaise traduction/définition, entrée dupliquée, …). In 1940 Bittner became the lab's Assistant Director, where he remained until December 1942. It is quite unlikely that the methods used, except in rare cases in statistical and genetic studies of cancer in man, have as yet reached the degree of sophistication necessary to yield satisfactory data. itty bitty Extremely small; tiny. Please enable it to take advantage of the complete set of features! Finden Sie hier Traueranzeigen, Todesanzeigen und Beileidsbekundungen aus Ihrer Tageszeitung oder passende Hilfe im Trauerfall. had a similar success in imaging the "milk factor" in murine mammary adenocarcinomas cells (3).



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